Progression of Liver Disease
There are many different types of liver disease. But no matter what type you have, the damage to your liver is likely to progress in a similar way. Whether your liver is infected with a virus, injured by chemicals, or under attack from your own immune system, the basic danger is the same – that your liver will become so damaged that it can no longer work to keep you alive.
Your liver helps fight infections and cleans your blood. It also helps digest food and stores energy for when you need it. A healthy liver has the amazing ability to grow back, or regenerate, when it is damaged. Anything that keeps your liver from doing its job – or from growing back after injury – may put your life in danger
In the early stage of any liver disease, your liver may become inflamed. It may become tender and enlarged. Inflammation shows that your body is trying to fight an infection or heal an injury. But if the inflammation continues over time, it can start to hurt your liver permanently.
When most other parts of your body become inflamed, you can feel it – the area becomes hot and painful. But an inflamed liver may cause you no discomfort at all. If your liver disease is diagnosed and treated successfully at this stage, the inflammation may go away.
If left untreated, the inflamed liver will start to scar. As excess scar tissue grows, it replaces healthy liver tissue. This process is called fibrosis. (Scar tissue is a kind of fibrous tissue.)
Scar tissue cannot do the work that healthy liver tissue can. Moreover, scar tissue can keep blood from flowing through your liver. As more scar tissue builds up, your liver may not work as well as it once did. Or, the healthy part of your liver has to work harder to make up for the scarred part. If your liver disease is diagnosed and treated successfully at this stage, there’s still a chance that your liver can heal itself over time.
But if left untreated, your liver may become so seriously scarred that it can no longer heal itself. This stage – when the damage cannot be reversed – is called cirrhosis.
- Cirrhosis can lead to a number of complications, including liver cancer. In some people, the symptoms of cirrhosis may be the first signs of liver disease. You may bleed or bruise easily.
- Water may build up in your legs and/or abdomen.
- Your skin and eyes may take on a yellow color, a condition called jaundice.
- Your skin may itch intensely.
- In blood vessels leading to your liver, the blood may back up because of blockage. These blood vessels may burst.
- You may become more sensitive to medications and their side effects.
- You may develop insulin resistance and type-2 diabetes.
- Toxins may build up in your brain, causing problems with concentration, memory, sleeping, or other mental functions.